PLEASE NOTE : This is a development system.
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For Surrey PAD, please go to https://surreyccg.res-systems.net/PAD.
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Search Results : Diabetes Mellitus (Insulin Lispro - Humalog - Diabetes Mellitus)
Records returned : 76 (on 19 Apr 2025 at 21:25:20). Return to search results for ' Diabetes Mellitus '.
Drug
Indication
Status
Trust Alignment
Links
Restrictions/Comments
06.01.01
Insulin Lispro - Humalog
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form. Admelog (biosimilar insulin lispro) is lower cost and should be considered in preference to Humalog.
06.01.02
Green
Formulations :
- Modified release tablets
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Preferred
NOTE: 1g oridnary tablets are disproportionately expensive in primary care. 1g modified release tablets are recommended.
06.01.02
Green
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Preferred
06.01.02
Green
Formulations :
- Subcutaneous injection (sc)
ASPH
RSFT
SASH
SABP
Primary Care
Important
Preferred
Preferred GLP-1 for WEEKLY injection.
Green
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
Green
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Preferred
06.01.02
Green
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Preferred
06.01.02
Green
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
Green
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
06.01.01
Insulin Lispro - Lyumjev
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form.
06.01.01
Insulin Aspart - Trurapi
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Preferred
Prescribe by brand and state form. Lower-cost biosimilar. Preferred for new patients.
06.01.01
Insulin aspart - NovoRapid
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Biosimilar insulin aspart (Trurapi) should be used in preference to NovoRapid.
Prescribe by brand and state form.
06.01.01
Insulin glargine - Abasaglar
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form. Semglee (biosimilar) is a lower cost option for patients using a pre-filled pen.
06.01.01
Insulin Lispro - Admelog
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Biosimilar insulin Lispro (Admelog).
Prescribe by brand and state form.
06.01.01
Soluble insulin - Actrapid
(Insulin)
Green
Formulations :
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
06.01.01
Soluble insulin - Humulin S
(Insulin)
Green
Formulations :
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form.
06.01.01
Isophane Insulin - Insulatard
(Insulin)
Green
Formulations :
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form.
06.01.01
Isophane Insulin - Humulin I
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form.
06.01.01
Insulin glargine - Lantus
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form. Semglee (biosimilar) is a lower cost option for patients using a pre-filled pen. Lantus remains an option in existing patients and those preferring a reusable pen.
06.01.01
Insulin glargine - Semglee
(Insulin)
Green
Formulations :
- Pre-filled pen
ASPH
RSFT
SASH
SABP
Primary Care
Important
Preferred
Semglee (biosimilar insulin glargine) is the preferred brand for all new patients who require a pre-filled pen.
Prescribe by brand.
Note - Semglee is NOT available as cartridges for use in re-usable insulin pens.
06.01.01
Biphasic Isophane Insulin - Humulin M3
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form.
06.01.01
Biphasic Insulin Aspart - Novmix 30
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form.
06.01.01
Biphasic Lispro Insulin - Humalog Mix 25
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form.
06.01.01
Biphasic Lispro Insulin - Humalog Mix 50
(Insulin)
Green
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form.
06.01.01
Insulin glulisine - Apidra
(Insulin)
Green
Formulations :
- Pre-filled pen
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form.
SASH - restricted to diabetes team initiation only.
06.01.02
Green (see narrative)
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Oral semaglutide is not a preferred route due to poor availability and gastrointestinal side effects.
Use may be appropriate in a small cohort of patients where injection isn't suitable.
06.01.02
Green (see narrative)
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Reserve combination products for patients in whom separate components are less appropriate.
Existing patients would not be expected to change therapy unless appropriate to do so.
06.01.02
Green (see narrative)
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Empagliflozin is the preferred SGLT2.
Reserve combination products for patients in whom separate components are less appropriate.
06.01.02
Green (see narrative)
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Empagliflozin is the preferred SGLT-2.
Ertugliflozin is a treatment option.
Trusts restrict to diabetic team initiation only.
06.01.02
Green (see narrative)
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Type 2 diabetes.
Empagliflozin is the preferred SGLT-2
Dapagliflozin is not a preferred treatment option.
Trusts restrict to diabetic team initiation only.
06.01.02
Green (see narrative)
Formulations :
- Modified release
ASPH
RSFT
SASH
SABP
Primary Care
Important
Immediate release tablets are preferred
06.01.02
Green (see narrative)
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
Important
Exenatide is not a preferred treatment option. The preferred GLP-1 for WEEKLY injection is dulaglutide.
Prescribing may continue on existing patients.
06.01.02
Green (see narrative)
Formulations :
- Subcutaneous injection (sc)
ASPH
RSFT
SASH
SABP
Primary Care
Important
Dulaglutide is 1st line.
Semaglutide is the 2nd line option for WEEKLY injection. Max of 13 Ozempic pens per patient per year (1 pen is a 4 week supply).
06.01.02
Green (see narrative)
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Oral semaglutide is not a preferred route due to poor availability and gastrointestinal side effects.
Use may be appropriate in a small cohort of patients where injection isn't suitable.
06.01.02
Green (see narrative)
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Reserve combination products for patients in whom the separate components are less appropriate
06.01.02
Green (see narrative)
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Sitagliptin is 1st line. Only consider linagliptin in patients with rapidly deteriorating renal function where there is a risk that dose reduction of sitagliptin may not take place.
06.01.02
Green (see narrative)
Formulations :
- Oral solution
- Powder
ASPH
RSFT
SASH
SABP
Primary Care
Important
Oral solution should be reserved for patients with enteral feeding tubes or those unable to swallow tablets.
Sachets of powder for oral solution are preferred in patients with swallowing difficulties in primary care.
06.01.02
Green (see narrative)
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Reserve combination products for patients in whom the separate components are less appropriate
06.01.02
Green (see narrative)
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Not a preferred treatment option.
06.01.02
Green (see narrative)
Formulations :
- Subcutaneous injection (sc)
ASPH
RSFT
SASH
SABP
Primary Care
Important
Dulaglutide is the preferred weekly injection. Semaglutide is an alternative for weekly injections.
Tirzepatide is 3rd line where dulaglutide / semaglutide are unsuitable or unavailable.
06.01.02
Green (see narrative)
Formulations :
- Subcutaneous injection (sc)
ASPH
RSFT
SASH
SABP
Primary Care
Important
Preferred
Liraglutide is 1st-line for patients who wish to have a DAILY injection.
Dulaglutide is the preferred WEEKLY injection.
06.01.02
Green (see narrative)
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Inadequately controlled diabetes mellitus
06.01.01
Insulin detemir
(Insulin)
Green (see narrative)
Formulations :
- Pre-filled pen
- Cartridges
ASPH
RSFT
SASH
SABP
Primary Care
Important
Levemir (insulin detemir Penfill / FlexPen) is being discontinued. Supplies are expected to run out by Dec 2026. It is recommended that this is not initiated in new patients.
06.01.01
Insulin Aspart - Fiasp
(Insulin)
Blue
Formulations :
- Pre-filled pen
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand and state form.
SASH - restricted to diabetes team initiation only.
06.01.01
Insulin Glargine - Toujeo
(Insulin)
Blue
Formulations :
- Pre-filled pen
ASPH
RSFT
SASH
SABP
Primary Care
Important
Initiation by diabetes consultants or GPs with a specialist interest in diabetes. For use in poorly controlled patients.
06.01.01
Blue
Formulations :
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Initiation by diabetes team only. Usage is low but available for existing patients
06.01.01
Blue
Formulations :
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
Important
Initiation by diabetes team only
06.01.01
Insulin degludec
(Insulin)
Blue
Formulations :
- Pre-filled pen
- Cartridges
ASPH
RSFT
SASH
SABP
Primary Care
Important
Initiation by Diabetes team only. Prescribe by brand.
Insulin degludec is available in strengths of 100units/mL and 200units/mL - ensure correct strength is prescribed and dispensed
Red
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
Red
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
SASH restricted to specialist monogenic clinic for use in specific diabetic subtypes (unlicensed drug - hospital only prescribing)
02.05.01
06.01.04
Red
Formulations :
- Oral solution
ASPH
RSFT
SASH
SABP
Primary Care
Important
Always used in combination with chlorothiazide.
Red
Formulations :
- Capsules
ASPH
RSFT
SASH
SABP
Primary Care
Important
Unlicensed product
06.01.04
Red
Formulations :
- Oral solution
ASPH
RSFT
SASH
SABP
Primary Care
Important
Glucose 250mg per ml (75g in 300ml)
Not supplied by Pharmacy at SASH - ordered from NHS Procurement
06.01.02
N/A
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
N/A
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
N/A
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Not licensed in Type 1 diabetes. Not to be initiated in new Type 1 patients.
Shared care remains in place for existing patients only.
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Sotagliflozin is not yet available in the NHS. The NICE TA622 will not be implemented until the product is available. Place in therapy will also be determined at this time.
06.01.02
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Existing patients would not be expected to change therapy unless appropriate to do so.
06.01.02
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Existing patients would not be expected to change therapy unless appropriate to do so.
06.01.02
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Existing patients would not be expected to change therapy unless appropriate to do so.
06.01.02
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Sitagliptin is the preferred DPP4.
Reserve combination products for patients in whom separate components are less appropriate.
Existing patients would not be expected to change therapy unless appropriate to do so.
06.01.02
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Sitagliptin is the preferred DPP4.
Reserve combination products for patients in whom separate components are less appropriate.
Existing patients would not be expected to change therapy unless appropriate to do so.
06.01.02
06.01.04
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Empagliflozin is the preferred SGLT2.
Non Formulary
Formulations :
- Injection
ASPH
RSFT
SASH
SABP
Primary Care
06.01.01
Non Formulary
Formulations :
- Injection
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Not a cost-effective option. Prescribe as separate components.
02.05.01
06.01.04
Non Formulary
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
06.01.01
Soluble insulin - Humulin R
(Insulin)
Non Formulary
Formulations :
- Pre-filled pen
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
06.01.01
Non Formulary
Formulations :
- Cartridges
- Vials
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
See Below
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
06.01.02
See narrative
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
For information about the icons and status values within this site, please refer to the keys below.
Icon/Links Key
NFD1
Non formulary
NFD2
Not assessed for formulary status. Apply to APC / DTC before use.
CD
Controlled drug. Prescribing and/or storage requirements may apply
R
Restrictions apply
SA
Safety Alert
U
Unlicensed - no UK marketing license in place
Un
Off-label use. Not licensed for this indication.
NHSE
Treatment commissioned by NHS England
CDF
CDF
ICB
Treatment commissioned by the ICB
BlueTeq form to be completed
NICE
Traffic Light Status Key
Red
Amber
Green
Black
Amber Star
Green (see narrative)
Non Formulary
See Below
N/A
Blue
Green - Black
See narrative
Do not initiate in new patients