PAD - Prescribing Advisory Database
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PAD Profile : Insulin Glargine - Toujeo - Diabetes Mellitus

Keywords :
High-strength insulins, high strength insulins, lipohypertrophy, cutaneous amyloidosis
Brand Names Include :
Toujeo

Traffic Light Status

Status 1 of 1.

Status :
Blue
Important
Formulations :
  • Pre-filled pen
Important Information :
Initiation by diabetes consultants or GPs with a specialist interest in diabetes. For use in poorly controlled patients.
Trust Alignment :
Primary Care
ASPH
RSFT
SASH
SABP
Links :
Comments :
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Documents :

Guidelines

The following guidelines are available for this indication.

Other Drugs

Other Indications

Additional Documents

Committee Recommendations

Date
Committee Name
Narrative
14 July 2021
Surrey Heartlands Medicines Safety Committee (MSC)

MHRA Safety Alert

Cutaneous amyloidosis can be considered as a differential diagnosis to lipodystrophy when a patient presents with subcutaneous lumps at an insulin injection site.  Healthcare professionals are advised to ensure that all people who inject insulin are taught to check for signs of developing cutaneous amyloidosis or lipohypertrophy and that they should report any abnormalities to their healthcare professional.

Refer to the Cutaneous amyloidosis Guidance for Healthcare Professionals below

03 February 2016
Surrey & North West Sussex Area Prescribing Committee (formerly Prescribing Clinical Network)
The PCN recommends the use of Toujeo (insulin glargine 300units/ml) in type 2 diabetes in the following circumstances: A: To be initiated by diabetes consultants or those GPs with specialist interest in diabetes, only in those poorly controlled patients: Who do not reach their target HbA1c because of significant hypoglycaemia OR Who experience significant hypoglycaemia on Neutral Protamine Hagedorn (NPH) and insulin detemir or glargine (100units/ml) irrespective of the level of HbA1c OR Who cannot use the device needed to inject NPH and insulin detemir or glargine (100units/ml) but who could administer their own insulin safely and accurately if a switch to one of the long acting insulin analogues was made OR Who need help from a carer or healthcare professional to administer insulin injections and for whom having a 3 hour window for daily administration is essential. B: For those patients currently receiving Humulin R U-500, consider switch to Toujeo

Associated BNF Codes

06. Endocrine System
06.01.01. Insulin
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