PAD - Prescribing Advisory Database
PLEASE NOTE : This is a development system.

For Surrey PAD, please go to https://surreyccg.res-systems.net/PAD.

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PAD Profile : Ozanimod - Ulcerative colitis - moderately to severely active

Keywords :
NICE, TA828, sphingosine 1-phosphate (S1P) receptor modulator, UC, IBD, inflammatory bowel disease
Brand Names Include :
Zeposia

Traffic Light Status

Status 1 of 1.

Status :
Red
Formulations :
  • Capsules
Trust Alignment :
Primary Care
ASPH
RSCH
SASH
SABP
Links :
Comments :
No comments returned.
Documents :

Guidelines

No guidelines returned.

Other Drugs

Other Indications

Additional Documents

Committee Recommendations

Date
Committee Name
Narrative
04 October 2023
Surrey Heartlands Integrated Care System Area Prescribing Committee (APC)

The Surrey Heartlands Integrated Care System Area Prescribing Committee has agreed the reviewed and updated IBD immunomodulator pathway.

04 January 2023
Surrey & North West Sussex Area Prescribing Committee (formerly Prescribing Clinical Network)

The Surrey Heartlands integrated care system Area Prescribing Committee (APC) approves ozanimod as recommended by NICE TA828 as an option for treating moderately to severely active ulcerative colitis in adults, only if:
•    conventional treatment cannot be tolerated or is not working well enough, and infliximab is not suitable, or
•    biological treatment cannot be tolerated or is not working well enough, and
•    the company provides it according to the commercial arrangement.

Ozanimod for this indication will be considered as RED on the traffic light system (treatment should be initiated and continued by specialist clinicians).
Primary care prescribers should be aware that their patient is receiving this medicine and ensure that this is recorded on the patient’s medication screen as a hospital-only drug in line with guidance on the PAD. This will also alert the prescriber to potential side effects and interactions with other medicines prescribed in primary care. It will also ensure that GP records, which are accessed by other healthcare providers, are a true and accurate reflection of the patient’s medication

Associated BNF Codes

01. Gastro-Intestinal System
01.05.03. Drugs affecting immune response
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