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PAD Profile : Esketamine hydrochloride - Depression
Keywords :
Treatment resistant
Brand Names Include :
Spravato
Traffic Light Status
Status 1 of 1.
Guidelines
The following guidelines are available for this indication.
Other Drugs
Other Indications
- Wet age-related macular degeneration
- Lambert-Eaton myasthenic syndrome (LEMS)
- Respiratory distress in preterm neonates
- Pain
- Diabetic retinopathy
- Osteoarthritis
- Respiratory distress in preterm neonates
- Hepatic encephalopathy
- Travellers diarrhoea
- Penile rehabilitation
- Erectile dysfunction
- Cytomegalovirus
- Hyperuricaemia and Gout
- Vitreomacular traction
- Allergic rhinitis
- Renal dialysis
- Retinal Vein Occlusion
- Peripheral arterial disease
- Dysphagia
- Nursing (patient care)
- Diabetic macular oedema
- Diarrhoea
- Haemorrhoids
- Heart failure
- Oedema
- Lipid modification
- Nasal congestion
- Haemophilia
- Cataracts
- Branch retinal vein occlusion
- Low sexual desire in menopausal women
- Hypertension
- Hypertension
- Hypertension
- Bacterial infection
- Inflammatory bowel disease
- Psoriasis
- Atopic dermatitis
- Multiple sclerosis
- Myopic choroidal neovascularisation
- Cystic fibrosis
- Fungal infection
- Duchenne muscular dystrophy
- Multiple sclerosis
- Cystic fibrosis
- Hepatitis C
- Tuberculosis
- Hepatitis C
- Multiple sclerosis
- Tuberculosis
- Hepatitis C
- Hepatitis C
- Hepatitis C
- Metabolic disorders
- Haemophilia
- Cystic fibrosis
- Hepatitis C
- Systemic Lupus Erythematosus
- Hereditary angiodema
- Hepatitis C
- Inclusion body myositis
- Cytomegalovirus
- Asthma
- Hereditary angiodema
- Haemophilia
- Systemic Lupus Erythematosus
- Duchenne muscular dystrophy
- Hepatitis C
- Haemophilia
- Systemic Lupus Erythematosus
- Haemophilia
- Haemophilia
- Haemophilia
- Haemophilia
- Multiple sclerosis
- Hepatitis B
- Haemophilia
- Short bowel syndrome
- Pseudoaneurysm
- Haemophilia
- Any paediatric use
- von Willebrand deficiency
- Haemophilia
- Haemophilia
- Erectile dysfunction combination therapy
- Children and young people with Epilepsy
- Mental Health disorders
- Mental Health disorders
- Inflammatory bowel disease
- Acne
- Diabetes Mellitus
- Interface Prescribing Policy (IPP)
- Asthma
- Asthma
- Non-acne dermatological indications
- Anticoagulation reversal
- Mania
- Depression
- Restless Leg Syndrome
- von Willebrand deficiency
- Chronic Obstructive Pulmonary Disease (COPD)
- Chronic Obstructive Pulmonary Disease (COPD)
- Diabetes Mellitus
- Smoking cessation
- Immune thrombocytopenia
- Wet age-related macular degeneration
- Hyperkalaemia
- Bacterial skin and skin structure infections
- Cystic fibrosis
- Narcolepsy
- Thrombocytopenia
- Bacterial lung infection (non-cystic fibrosis)
- Lipid modification
- Opioid dependence
- Menopausal disorders
- Menopausal disorders
- All
- Raynaud's Phenomenon
- Chronic Obstructive Pulmonary Disease (COPD)
- Atopic dermatitis
- Psoriasis
- Clostridioides difficile
- Hereditary angiodema
- Covid-19
- Covid-19
- Covid-19
- Peanut allergy in children and young people
- Inflammatory bowel disease
- Chronic kidney disease in type 2 diabetes
- Growth failure - children
- Inflammatory bowel disease
- Diabetic macular oedema
- Wet age-related macular degeneration
- Diabetic macular oedema
- Acid Suppression (Children)
- Migraine (prevention)
- Urinary incontinence
- Immune thrombocytopenia
- Retinopathy of prematurity
- Type 1 Diabetes
- Pregnancy - Type 1 Diabetes
- Pregnancy - NON Type 1 Diabetes requiring insulin
- Type 2 Diabetes (Children and Young People)
- Glaucoma / ocular hypertension
- Dry eyes
- Vaginal atrophy
- Cancer
- Diarrhoea
- Inflammatory bowel disease
- Non-radiographic axial spondyloarthritis
- Photoaggravated dermatoses
- Photodermatoses
- Metabolic disorders
- Insomnia in adults
- Cardiomyopathy
- Epidermolysis bullosa
- Photoaggravated dermatoses
- Psoriasis
- Psoriatic arthritis
- Photodermatoses
- Photodermatoses
- Photoaggravated dermatoses
- Catheter maintenance solutions
- Dry eyes
- Dry eyes
- Dry eyes
- Dry eyes
- Dry eyes
- Dysphagia
- Prurigo nodularis
- Vitamin D deficiency and insufficiency
- Osteoporosis
- Migraine (prevention)
- Pain
- Ankylosing spondylitis
- Axial spondyloarthritis
- Pustular psoriasis
- Mucus clearance
- Atopic dermatitis
- Alopecia
- Asthma
- Chronic Obstructive Pulmonary Disease (COPD)
- Smoking cessation
- Pain
- Homozygous familial hypercholesterolaemia
- Asthma
- Chronic Obstructive Pulmonary Disease (COPD)
- Metabolic disorders
- Conscious sedation
- Premedication
- post Bariatric surgery
- Erectile dysfunction
- Parkinson's disease
- Myasthenia gravis
- Bacterial infection
- Bacterial infection
- Bacterial infection
- Bacterial infection
- Bacterial infection
- Bacterial infection
- Bacterial infection
- Tuberculosis
- Tuberculosis
- Tuberculosis
- Covid-19
- Inflammatory bowel disease
- Rehydration in short bowel syndrome
- Minor digestive complaints
- Haemorrhoids
- Haemorrhoids
- Menopausal disorders
- Menopausal disorders
- Menopausal disorders
- Menopausal disorders
- Menopausal disorders
- Menopausal disorders
- Menopausal disorders
- Menopausal disorders
- Nutrition (Infant)
- Nutrition (Infant)
- Nutrition (Infant)
- Nutrition (Infant)
- Nutrition (Infant)
- Nutrition (Infant)
- Nutrition (Infant)
- Nutrition (Infant)
- Nutrition (Infant)
- Nutrition (Infant)
- Nutrition (Infant)
- Nausea and vomiting
- Agitation in mania and psychotic disorders
- Schizophrenia
- Intraoperative mydriasis / prevention of miosis
- Stoma
- Arrhythmias
- Acute coronary syndrome
- Acute coronary syndrome
- Inotropic support
- IV catheter maintenance
- Cardiopulmonary resuscitation
- Hepatitis D
- Hypertension (severe / crisis)
- Heart failure
- Oedema
- Hypotension
- Tissue glue / suture support
- Diagnosis of Brugada syndrome
- Heparin induced thrombocytopenia
- HIV infection
- Stoma
- Stoma
- Stoma
- Stoma
- Stoma
- Stoma
- Stoma
- Stoma
- Stoma
- Smoking cessation
- Endometriosis
- Surgical diagnostic
- Ocular surgery
- Chronic Obstructive Pulmonary Disease (COPD)
- Growth failure - adults
- Growth failure - children
- Oesophagitis (inducing remission)
- Uterine fibroids
- Overactive bladder (adults)
- Retinal Vein Occlusion
- Hidradenitis suppurativa
- Alzheimers disease
- Alzheimers disease
- Osteoporosis
- Allergen immunotherapy
- Premedication
- Local anaesthesia
- Hereditary angiodema
- Hereditary angiodema
- Status epilepticus
- Type 1 Diabetes
- Wet age-related macular degeneration
- Metabolic disorders
- Copper deficiency
- Relapsing-remitting multiple sclerosis
- Analgesia / anaesthesia
- Dravet syndrome
- Obstetric analgesia
- Methotrexate-induced renal dysfunction
- Local anaesthesia
- Hepatic encephalopathy
- Procedural pain relief (excluding obstetrics and p
- Unlicensed Medicines
- Monkeypox
- Otitis externa
- Otitis externa
- Otitis externa
- Otitis externa
- Otitis externa
- Earwax removal
- Earwax removal
- Cytomegalovirus
- Cardiomyopathy
- Menorrhagia
- Nasal staphylococci eradication
- Epistaxis
- Epistaxis
- ENT surgery
- Oral hygiene
- Paroxysmal nocturnal haemoglobinuria
- Necrotising enterocolitis (NEC)
- Monkey pox
- Mild inflammatory skin disorders
- Outpatient Parenteral Antimicrobial Therapy (OPAT)
- Interventional radiology
- Endoscopic procedures
- Botulism type A, B and E
- Methanol / ethylene glycol (antifreeze) poisoning
- Methanol / ethylene glycol (antifreeze) poisoning
- Methotrexate induced renal dysfunction
- Severe systemic local anaesthetic toxicity
- Methaemoglobinaemia
- Organophosphorus or carbamate insecticide poisonin
- Thallium radiation
- Heavy metal poisoning
- Cyanide poisoning
- Heavy metal poisoning
- Heavy metal poisoning
- 5-Fluorouracil or capecitabine toxicity
- Envenomation by Vipera Berus
- Contraception
- Prostate cancer
- Multiple sclerosis
- Conscious sedation
- Surgical diagnostic
- Pre-operative / bridging therapy
- Interventional radiology
- Intravenous fluid therapy
- Stress test
- Breath test
- Vaccinations
- Endoscopic procedures
- Hyperphosphataemia
- Endoscopic procedures
- Polycythaemia, Thrombocythaemia & Myelofibrosis
- Wound debridement
- Interventional radiology
- Vaccinations
- Renal dialysis
- Local anaesthesia
- Interventional radiology
- Primary biliary cholangitis
- Hypotension
- Type 1 Diabetes
- Type 2 Diabetes (Adults)
- Pregnancy - NON Type 1 Diabetes requiring insulin
- Epilepsy
- Insomnia in adults
- Dysphagia
- Multiple sclerosis
Additional Documents
No additional documents returned.
Committee Recommendations
Date
Committee Name
Narrative
05 February 2025
Surrey Heartlands Integrated Care System Area Prescribing Committee (APC)
The Surrey Heartlands Integrated Care System Area Prescribing Committee (APC) has confirmed a NON-FORMULARY traffic light status for esketamine for treating major depressive disorder in adults at imminent risk of suicide.
This decision is in view of the NICE terminated Technology Appraisal for esketamine for this indication
Associated BNF Codes
04. Central Nervous System
04.03.04. Other antidepressant drugs