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PAD Profile : Domperidone - Nausea and vomiting (Parkinson's disease)
Traffic Light Status
Status 1 of 1.
Guidelines
No guidelines returned.
Other Drugs
No drugs returned.
Other Indications
- Lactation stimulation
- Nausea and vomiting (pregnancy)
- Parkinson's Disease (apomorphine pre-treatment)
Additional Documents
Committee Recommendations
The Surrey & North West Sussex Area Prescribing Committee recommends the off label use of domperidone for the treatment of nausea & vomiting when used in Parkinson's Disease patients, as recommended within NICE Clinical Knowledge Summaries (CKS) https://cks.nice.org.uk/parkinsons-disease
Treatment duration is restricted to a maximum of one week in all patients*.
Prescribers should ensure that the patient understands the risks and consents to using domperidone off-label noting the MHRA drug safety alert (updated December 2019)
Domperidone will be considered GREEN on the traffic light system for this indication.
*MHRA drug safety update (December 2019) https://www.gov.uk/drug-safety-update/domperidone-for-nausea-and-vomiting-lack-of-efficacy-in-children-reminder-of-contraindications-in-adults-and-adolescents