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Search Results : Inflammatory bowel disease (Vedolizumab - Inflammatory bowel disease)
Records returned : 40 (on 21 Nov 2024 at 17:54:48). Return to search results for ' Inflammatory bowel disease '.
Drug
Indication
Status
Trust Alignment
Links
Restrictions/Comments
01.05.03
Red
Formulations :
- Infusion
- Subcutaneous injection (sc)
ASPH
RSFT
SASH
SABP
Primary Care
Important
Not 1st line.
Only in patients where steroids and/or TNF inhibitor not effective / appropriate
01.05.02
05.03.06
06.03.02
Green
Formulations :
- Foam enema
ASPH
RSFT
SASH
SABP
Primary Care
Important
Steroid safety considerations
01.05.02
11.04.01
Green
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Tablets can be dispersed for immediate administration.
Green
Formulations :
- Soluble tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Paediatrics only at SASH.
Paediatrics and oncology at ASPH
Green
Formulations :
- Oral solution
ASPH
RSFT
SASH
SABP
Primary Care
Important
Paediatric doses and NG/NJ tube only
01.05.01
Green (see narrative)
Formulations :
- Gastro-resistant tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Preferred
Ulcerative colitis only. GP may initiate following diagnosis or advice from specialist. Refer to the Ulcerative Colitis pathway.
Prescribe by brand.: Octasa or Salofalk gastro resistant tablets (or Salofalk granules) are 1st line for new patients
Asacol tablets are non-formulary
Green (see narrative)
Formulations :
- Suppositories
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative colitis only. GP may initiate following diagnosis or advice from specialist. Refer to the Ulcerative Colitis pathway.
Prescribe by brand: Octasa, Salofalk, Pentasa
Green (see narrative)
Formulations :
- Modified release tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative colitis only. GP may initiate following diagnosis or advice from specialist. Refer to the Ulcerative Colitis pathway.
Mezevant XL - Reserve for patients with a high pill burden.
Green (see narrative)
Formulations :
- Granules (slow release)
- Modified release tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Preferred
Ulcerative colitis only. GP may initiate following diagnosis or advice from specialist. Refer to the Ulcerative Colitis pathway.
Prescribe by brand: Salofalk granules are a 1st-line option for new patients.
Pentasa modified-release tablets and granules for patients who require upper GI release.
Green (see narrative)
Formulations :
- Enema
- Foam enema
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative colitis only. GP may initiate following diagnosis or advice from specialist. Refer to the Ulcerative Colitis pathway.
Prescribe by brand: Pentasa / Salofalk enema
01.05.03
08.02.01
Amber
Formulations :
- Oral suspension
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
08.02.01
Amber
Formulations :
- Oral suspension
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Tablets and oral suspension are NOT bioequivalent. Do not confuse with mercaptamine (similar name).
01.05.03
10.01.03
13.05.03
Amber
Formulations :
- Injection
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
DO NOT prescribe or supply 10mg tablets.
WEEKLY dose frequency.
Advise patients to carry the patient alert card / book
01.05.01
10.01.03
Amber
Formulations :
- Oral suspension
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Amber
Formulations :
- Gastro-resistant tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Enteric coated tablets are significantly more expensive. Reserve for patients unable to tolerate plain tablets.
Amber
Formulations :
- Suppositories
ASPH
RSFT
SASH
SABP
Primary Care
01.05.03
10.01.04
Amber
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Off-label use in combination with azathioprine and mercaptopurine
01.05.03
08.02.02
10.01.03
11.08.01
13.05.03
Red
Formulations :
- Oral solution
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative colitis only. Prescribe by brand
Ulcerative colitis only
01.05.03
10.01.03
11.08.03
13.05.03
Red
Formulations :
- Subcutaneous injection (sc)
ASPH
RSFT
SASH
SABP
Primary Care
Important
Adults only.
Prescribe by brand.
01.05.03
10.01.03
13.05.02
13.05.03
Red
Formulations :
- Subcutaneous injection (sc)
- Intravenous infusion
ASPH
RSFT
SASH
SABP
Primary Care
Important
Prescribe by brand
01.05.03
10.01.03
13.05.03
Red
Formulations :
- Subcutaneous injection (sc)
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative Colitis in Adults only.
Prescribe by brand.
Red
Formulations :
- Subcutaneous injection (sc)
- Intravenous infusion
ASPH
RSFT
SASH
SABP
Primary Care
Important
Adults only.
Red
Formulations :
- Subcutaneous injection (sc)
- Intravenous infusion
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative Colitis - adults only.
01.05.02
05.03.06
06.03.02
Red
Formulations :
- Modified release capsules
ASPH
RSFT
SASH
SABP
Primary Care
Important
Steroid safety considerations
3mg MR capsules - gastroenterology team only
01.05.03
10.01.03
13.05.03
Red
Formulations :
- Modified release tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative colitis in Adults only.
01.05.03
10.01.03
13.05.02
13.05.03
Red
Formulations :
- Subcutaneous injection (sc)
- Intravenous infusion
ASPH
RSFT
SASH
SABP
Primary Care
Important
Adults only
Red
Formulations :
- Capsules
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative Colitis - adults only.
Red
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative colitis only
NICE guidance applies to Ulcerative Colitis patients only
01.05.03
10.01.03
Red
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative colitis - adults only
01.05.03
10.01.03
Red
Formulations :
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative colitis - adults only
01.05.03
08.02.02
10.01.03
11.08.01
13.05.03
Red
Formulations :
- Capsules
- Intravenous infusion
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative colitis only. Prescribe by brand
N/A
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
N/A
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
01.05.02
05.03.06
06.03.02
N/A
Formulations :
- Suppositories
ASPH
RSFT
SASH
SABP
Primary Care
Important
Steroid safety considerations
Not assessed for formulary status. Applications for formulary entry via APC.
Non Formulary
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
Important
For Crohn's disease only
01.05.01
Non Formulary
Formulations :
- Capsules
- Tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Licensed in mild ulcerative colitis
01.05.01
Non Formulary
Formulations :
- Not Specified
ASPH
RSFT
SASH
SABP
Primary Care
01.05.02
11.04.01
Non Formulary
Formulations :
- Gastro-resistant tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Enteric coated tablets - non-formulary
01.05.01
Non Formulary
Formulations :
- Gastro-resistant tablets
ASPH
RSFT
SASH
SABP
Primary Care
Important
Ulcerative colitis only. GP may initiate following diagnosis or advice from specialist. Refer to the Ulcerative Colitis pathway.
Asacol 400mg gastro resitsant tablets have been discontinued. The 800mg tablets are non-formulary.
01.05.02
11.04.01
Non Formulary
Formulations :
- Foam enema
ASPH
RSFT
SASH
SABP
Primary Care
Important
Budesonide rectal foam is preferred.
Steroid safety considerations
For information about the icons and status values within this site, please refer to the keys below.
Icon/Links Key
NFD1
Non formulary
NFD2
Not assessed for formulary status. Apply to APC / DTC before use.
CD
Controlled drug. Prescribing and/or storage requirements may apply
R
Restrictions apply
SA
Safety Alert
U
Unlicensed - no UK marketing license in place
Un
Off-label use. Not licensed for this indication.
NHSE
Treatment commissioned by NHS England
CDF
CDF
ICB
Treatment commissioned by the ICB
BlueTeq form to be completed
NICE
Traffic Light Status Key
Red
Amber
Green
Black
Amber Star
Green (see narrative)
Non Formulary
See Below
N/A
Blue
Green - Black
See narrative
Do not initiate in new patients