The Surrey Heartlands Integrated Care System Area Prescribing Committee (APC) agreed a change in fidaxomicin traffic light status from Blue to GREEN.

This is to facilitate the prescribing of fidaxomicin following the recurrence of C diff infection within 12 weeks of a previous infection (as per NICE NG199).

For any patient requiring a liquid preparation, fidaxomicin granules should be prescribed.  The APC notes that although current NICE guidelines recommend vancomycin first line, it is recognised that this was based on cost and in exceptional cases when a liquid is required, fidaxomicin granules are appropriate to prescribe as a licensed preparation that supports timely treatment.

SUPPLY:

Vancomycin and fidaxomicin are not routinely stocked in community pharmacies but are usually obtainable on next-day delivery. However, at weekends and bank holidays, a local arrangement has been put in place whereby a small number of pharmacies will hold supplies. Please refer to the document below called "Supply of oral vancomycin and fidaxomicin for treating Clostridioides difficile in Primary Care - Mar 23"