PAD - Prescribing Advisory Database
PLEASE NOTE : This is a development system.

For Surrey PAD, please go to https://surreyccg.res-systems.net/PAD.

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PAD Profile : Vancomycin hydrochloride - Clostridioides difficile

Keywords :
c.diff infection, C.difficile infection, clostridium difficile infection, antibiotic, antibacterial, glycopeptide
Brand Names Include :
Vancocin, Matrigel

Traffic Light Status

Status 1 of 1.

Status :
Green
Important
Formulations :
  • Capsules
Important Information :
Restricted Use - for use when indicated by local trust antimicrobial guidelines, NICE condensed summary table of antimicrobial guidance or specialist microbiology recommendation. The APC notes that although current NICE guidelines recommend vancomycin first line for treatment of C diff, it is recognised that this was based on cost and in exceptional cases when a liquid is required, fidaxomicin granules are appropriate to prescribe as a licensed preparation that supports timely treatment.
Trust Alignment :
Primary Care
ASPH
RSFT
SASH
SABP
Links :
Comments :
No comments returned.
Documents :

Guidelines

No guidelines returned.

Other Drugs

Other Indications

Additional Documents

Committee Recommendations

Date
Committee Name
Narrative
03 August 2022
Surrey Heartlands Integrated Care System Area Prescribing Committee (APC)

ADVICE UPDATE:             
The Surrey Heartlands Integrated Care System Area Prescribing Committee (APC) agreed the following in relation to prescribing of C.difficile treatments after a positive test for C.difficile.
Vancomycin oral treatment 

  • GREEN traffic light status for treatment of C.diff. in adults as per NICE clinical guideline.  
  • BLUE (on recommendation) traffic light status for children.  

For any patient requiring a liquid preparation, fidaxomicin granules should be prescribed.  The APC notes that although current NICE guidelines recommend vancomycin first line, it is recognised that this was based on cost and in exceptional cases when a liquid is required, fidaxomicin granules are appropriate to prescribe as a licensed preparation that supports timely treatment.

Follow link to Fidaxomicin information https://surreyccg.res-systems.net/PAD/Search/DrugConditionProfile/6508

SUPPLY

Vancomycin and fidaxomicin are not routinely stocked in community pharmacies but are usually obtainable on next-day delivery. However, at weekends and bank holidays, a local arrangement has been put in place whereby a small number of pharmacies will hold supplies. Please refer to the document below called "Supply of oral vancomycin and fidaxomicin for treating Clostridioides difficile in Primary Care - Mar 23"

Associated BNF Codes

05. Infections
05.01.07. Some other antibacterials
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