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PAD Profile : Doxylamine succinate/pyridoxine hydrochloride - Nausea and vomiting (pregnancy)
Traffic Light Status
Status 1 of 1.
- Gastro-resistant tablets
Guidelines
The following guidelines are available for this indication.
Other Drugs
- Domperidone
- Cyclizine hydrochloride
- Promethazine teoclate
- Promethazine hydrochloride
- Prochlorperazine maleate
- Metoclopramide hydrochloride
- Ondansetron hydrochloride
Other Indications
No indications returned.
Additional Documents
No additional documents returned.
Committee Recommendations
The Surrey Heartlands APC approved doxylamine with pyridoxine for use in nausea and vomiting in pregnancy, acknowledging that the drug is licensed for this indication.
However, it was agreed that it should only be considered after a trial of a more established drug (off-label cyclizine, promethazine, prochlorperazine or chlorpromazine).
This drug has not yet been evaluated by NICE or the Surrey and Sussex Prescribing Clinical Network (PCN). As such, advice regarding safety, effectiveness (including cost-effectiveness) and its place in therapy is yet to be determined. It is recommended that clinicians contact their medicines management team for further information and advice before prescribing this drug.
It is expected that an evaluation of this drug will be completed by February 2019, after which further information will be provided.