The Surrey Heartlands Integrated Care System Area Prescribing Committee approves the prescribing of mexiletine for the management of drug resistant ventricular arrhythmia when initiated and continued by a specialist.

The APC recommend a RED traffic light status for the use of mexiletine for this indication.

All patients currently being prescribed mexiletine in primary care should be referred into a cardiologist for specialist review. Responsibility for prescribing must remain with the specialist.

Patients currently prescribed Namuscla® for the management of drug resistant arrhythmias should be reviewed by specialists to consider switching to the products licensed for ventricular arrhythmias noting that there isn’t an exact equivalent dose.