Fludrocortisone, although unlicensed for this use, is recommended for the treament of postural hypotension in Parkinson's Disease. Refer to the SPC for clinical particulars including contraindications and interactions with other medicines.

Fludrocortisone should only be continued or initiated on request from a Parkinson's specialist and only after a review of existing medicines to address any potential pharmalogical causes for the hypotension (including antihypertensives, dopaminergics, anticholinergics, antidepressants).

Midodrine may be considered (2nd line after fludrocortisone) for the treatment of orthostatic hypotension in patients with Parkinson's Disease.
Again, see the Midodrine SPC for details of contraindications and monitoring requirements.