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PAD Profile : Tapentadol hydrochloride - Pain (non-malignant) Important
Traffic Light Status
Status 1 of 1.
Guidelines
No guidelines returned.
Other Drugs
- Oxycodone
- Co-codamol (Codeine phosphate/paracetamol)
- Tramadol hydrochloride
- Tramadol hydrochloride
- Codeine phosphate
- Buprenorphine
- Morphine sulfate
- Pregabalin
- Gabapentin
- Meptazinol hydrochloride
- Co-dydramol (Dihydrocodeine/paracetamol)
Other Indications
No indications returned.
Additional Documents
Committee Recommendations
The APC supports the use of tapentadol SR as a treatment option for the management of severe persistent non-malignant pain in adults after assessment and recommendation by a pain specialist for patients not responding to / not tolerating morphine OR oxycodone.
Due to the similar mode of action and relative efficacy of tapentadol compared with tramadol, it would be appropriate to have tried tramadol before initiating tapentadol.
Tapentadol SR will be considered as BLUE (no information sheet) on the traffic light system.
Please be aware of the MHRA drug safety update (January 2019- attached below) in relation to potential increase in seizure risk in patients taking other medicines